Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535908 | 0.78 | CHRNB2 (0.34) | MAPK1L3MBTL1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL9701397 | 0.77 | CA1 (0.33) | MAPTALDH1A1HCRTR1HCRTR2HTT | |
| SCHEMBL9701430 | 0.73 | CA1 (0.33) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL9700197 | 0.72 | MAOB (0.32) | MAPTALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL9702700 | 0.70 | SIGMAR1 (0.33) | ALDH1A1 | |
| SCHEMBL9702241 | 0.67 | RAB9A (0.33) | ALDH1A1KDM4ELMNARAB9ACYP3A4 | |
| SCHEMBL7902260 | 0.65 | CYP1A2 (0.35) | MAPTALDH1A1KDM4EMAPK1L3MBTL1 | |
| SCHEMBL7902256 | 0.65 | CYP1A2 (0.35) | MAPTALDH1A1KDM4EMAPK1L3MBTL1 | |
| SCHEMBL9702570 | 0.65 | MAPT (0.42) | MAPTALDH1A1HTTKDM4EMAPK1 | |
| SCHEMBL9702143 | 0.62 | MAOB (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013860-A1 | NEW 4,5,6,7-TETRAHYDRO-IMIDAZO-[4,5,lJK][1,4]-BENZODIAZEPINE-2-(1H)-THIONES, A METHOD OF PREPARING THEM AS WELL AS DRUGS CONTAINING THEM, AND INTERMEDIATES FOR THE PREPARATION OF THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-20 | — | — | WO | disclosed |