SCHEMBL9702362

SCHEMBL9702362

CCCCc1c(F)c(F)c(S(=O)(=O)O)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CA2 P00918 3/20 0.33
CA1 P00915 2/20 0.33
CA12 O43570 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.32
FFAR1 O14842 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8736500 0.93 FAAH (0.35) CA2CA1TYMP
SCHEMBL13713627 0.90 FFAR1 (0.34) HCAR2NPC1HPGDMAPK1HTT
SCHEMBL20080940 0.85 CA1 (0.35) CA2CA1CA12CA7CA9
Ammonia Solution, Strong SCHEMBL29155301 0.82 FAAH (0.33) CA2CA1TYMP
SCHEMBL13925009 0.81 CA2 (0.52) CA2CA1CA12CA7CA9
SCHEMBL20362700 0.79 CA1 (0.35) CA2CA1CA12CA7CA9
SCHEMBL13243398 0.77 S1PR3 (0.37) HPGDMAPK1
Butylamine SCHEMBL17273600 0.77 CA1 (0.37) CA2CA1CA12CA7CA9
Butylamine SCHEMBL28996479 0.77 CA1 (0.37) CA2CA1CA12CA7CA9
SCHEMBL8165780 0.76 NPC1 (0.39) HCAR2NPC1HPGDMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992011400-A1 AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE, AN ALKANOL HAVING 1-3 CARBON ATOMS AND 2-METHYL-2-PROPANOL ALLIED-SIGNAL INC. (US) 1992-07-09 WO disclosed