SCHEMBL8736500

SCHEMBL8736500

CCCCCCCCCCCCCc1c(F)c(F)c(S(=O)(=O)O)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
S1PR2 O95136 2/20 0.34
S1PR1 P21453 2/20 0.34
S1PR3 Q99500 2/20 0.34
TYMP P19971 2/20 0.33
EPHX1 P07099 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GPR35 Q9HC97 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
ALOX5 P09917 4/20 0.33
MPEG1 Q2M385 3/20 0.33
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9702362 0.93 HCAR2 (0.33) CA1CA2TYMP
Ammonia Solution, Strong SCHEMBL29155301 0.90 FAAH (0.33) FAAHCA1CA2S1PR2S1PR1
SCHEMBL13243398 0.84 S1PR3 (0.37) S1PR2S1PR1S1PR3THRBALOX5
SCHEMBL13713627 0.83 FFAR1 (0.34) ALDH1A1
SCHEMBL13254421 0.82 CA2 (0.49) CA1CA2
SCHEMBL20080940 0.81 CA1 (0.35) CA1CA2
SCHEMBL28172757 0.81 S1PR2 (0.33) FAAHCA1CA2S1PR2S1PR1
SCHEMBL149531 0.81 S1PR2 (0.41) S1PR2S1PR1S1PR3ALDH1A1MAPT
SCHEMBL7787204 0.81 CA1 (0.38) CA1CA2S1PR2S1PR1S1PR3
SCHEMBL29666515 0.81 S1PR2 (0.41) S1PR2S1PR1S1PR3ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9081277-B2 Actinic-ray- or radiation-sensitive resin composition, actinic-ray- or radiation-sensitive film therefrom and method of forming pattern using the composition FUJIFILM CORPORATION (JP) 2015-07-14 US disclosed
US-20120129100-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST FILM AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120129100-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST FILM AND PATTERN FORMING METHOD USING THE SAME ACTR8, RAD51, ACTR2 FAAH 398/4885CA1 1209/4885CA2 4062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.