Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GCK | P35557 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700407 | 0.84 | IDO1 (0.41) | ALDH1A1KDM4EHTTMAPTSMN1; SMN2 | |
| SCHEMBL9701382 | 0.82 | SMN1; SMN2 (0.42) | ALDH1A1KDM4ETSHRMAPTSMN1; SMN2 | |
| SCHEMBL9700679 | 0.81 | MAOA (0.37) | KDM4EMAPTKMT2AGCK | |
| SCHEMBL9702587 | 0.80 | ALDH1A1 (0.41) | XDHALDH1A1KDM4EHTTTSHR | |
| SCHEMBL9700701 | 0.79 | NOTUM (0.41) | ALDH1A1KDM4EMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL9526113 | 0.79 | MAPT (0.41) | ALDH1A1KDM4EHTTTSHRMAPT | |
| SCHEMBL9528770 | 0.77 | KDM4E (0.48) | ALDH1A1KDM4ETSHRMAPTSMN1; SMN2 | |
| SCHEMBL9701387 | 0.76 | CYP2C9 (0.47) | XDHSMN1; SMN2LMNAHPGDCYP1A2 | |
| SCHEMBL9701671 | 0.76 | BRD4 (0.42) | ALDH1A1KDM4EHTTGAALMNA | |
| SCHEMBL9700756 | 0.76 | SNCA (0.37) | ALDH1A1KDM4EHTTTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |