Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700772 | 0.80 | XDH (0.35) | ALDH1A1HTTKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL9588370 | 0.76 | KDM4E (0.40) | ALDH1A1HTTKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7644729 | 0.76 | PDE5A (0.47) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL9525926 | 0.76 | CYP2C9 (0.31) | ALDH1A1HTTKDM4ETSHRMAPT | |
| SCHEMBL9530230 | 0.74 | MDM2 (0.41) | ALDH1A1HTTKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL9702603 | 0.72 | — | — | |
| SCHEMBL9701387 | 0.72 | CYP2C9 (0.47) | SMN1; SMN2HPGDPOLBLMNAXDH | |
| SCHEMBL9535284 | 0.72 | KDM4E (0.41) | KDM4EGAAPOLB | |
| SCHEMBL9701382 | 0.70 | SMN1; SMN2 (0.42) | ALDH1A1KDM4ETSHRSMN1; SMN2MAPT | |
| SCHEMBL9700783 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |