Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529353 | 0.82 | CYP2C9 (0.34) | CYP2C9MOGAT2MAPTKDM4EALDH1A1 | |
| SCHEMBL9702558 | 0.78 | ALDH1A1 (0.41) | MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL9700651 | 0.77 | MAPT (0.35) | CYP2C9MOGAT2MAPTKDM4EALDH1A1 | |
| SCHEMBL9702587 | 0.76 | ALDH1A1 (0.41) | MAPTMAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL9526401 | 0.74 | PTPN1 (0.36) | CYP2C9MOGAT2MAPT | |
| SCHEMBL9701582 | 0.74 | GCGR (0.39) | CYP2C9MOGAT2MAPTKDM4EALDH1A1 | |
| SCHEMBL9700772 | 0.73 | XDH (0.35) | CYP2C9MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL9700644 | 0.73 | PDE5A (0.38) | MAPTKDM4EALDH1A1 | |
| SCHEMBL9528770 | 0.72 | KDM4E (0.48) | MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL9525805 | 0.72 | CDC7 (0.36) | CYP2C9MOGAT2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |