Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535284 | 0.79 | KDM4E (0.41) | — | |
| SCHEMBL9754365 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HPGDMAPT | |
| SCHEMBL9754396 | 0.76 | ACVR1 (0.42) | ALDH1A1HPGDMAPT | |
| SCHEMBL9754436 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL9754463 | 0.72 | PTGER3 (0.39) | — | |
| SCHEMBL9700691 | 0.72 | PTGS2 (0.35) | ALDH1A1MAPT | |
| SCHEMBL9700679 | 0.71 | MAOA (0.37) | MAOBMAPT | |
| SCHEMBL9539748 | 0.70 | FASN (0.46) | MAOBTNIKALDH1A1HPGD | |
| SCHEMBL9702588 | 0.70 | ALPL (0.32) | ALDH1A1MAPT | |
| SCHEMBL9251638 | 0.70 | PTGER3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | claimed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |