Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526262 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9526447 | 0.78 | GAA (1.00) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL27154849 | 0.72 | PIM1 (0.62) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701913 | 0.72 | KDM4E (0.53) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701832 | 0.69 | KDM4E (0.77) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL10888666 | 0.69 | KDM4E (0.68) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL7260450 | 0.68 | KDM4E (0.70) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL12303123 | 0.67 | SLC6A2 (0.63) | ALDH1A1SLC6A2SLC6A4SLC6A3MAPK1 | |
| SCHEMBL4673334 | 0.67 | NPC1 (0.47) | GAASLC6A2SLC6A4 | |
| SCHEMBL7646373 | 0.66 | L3MBTL1 (0.54) | ALDH1A1KDM4EGLAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |