Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10442359 | 0.98 | KDM5B (0.33) | KDM5BCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL6184054 | 0.80 | CHRNB2 (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3836275 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL28026139 | 0.77 | CYP2D6 (0.33) | CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL491239 | 0.76 | TGFBR1 (0.44) | — | |
| SCHEMBL10861332 | 0.76 | FOLH1 (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL9701318 | 0.75 | PGR (0.36) | KDM5B | |
| SCHEMBL9702897 | 0.75 | USP2 (0.32) | KDM5B | |
| Hydrochloric Acid SCHEMBL9702826 | 0.75 | TGFBR1 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL4661689 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132454-A | Antihypoxic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5066677-A | Antihypoxic agents, treatment of disorders resulting from reduced oxygen supply to brain | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0387074-A2 | Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |