Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419847 | 0.80 | EPHX2 (0.41) | CHRM2GABRA1GABRB2RAB9A | |
| SCHEMBL9702939 | 0.79 | HCRTR1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL11967082 | 0.78 | RAB9A (0.40) | SCN9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10418865 | 0.77 | PPARG (0.34) | GPR119PPARGPPARA | |
| SCHEMBL9704923 | 0.72 | CHRM2 (0.52) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2300245 | 0.72 | GPR119 (0.39) | SCN9ACHRM2CHRM4CHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9702684 | 0.72 | CHRM2 (0.51) | SCN9ACHRM2CHRM4CHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9702698 | 0.72 | CHRM2 (0.51) | SCN9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2356574 | 0.71 | PLAT (0.45) | SCN9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9703140 | 0.68 | GABRA1 (0.37) | GABRA1GABRA3GABRB2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259621-B1 | PIPERIDINE COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-11-25 | — | — | EP | disclosed |
| US-4933353-A | ALZHEIMER*S DISEASE | A/S FERROSAN (DE) | 1990-06-12 | — | — | US | disclosed |
| US-4837241-A | TREATMENT OF ALZEHEIMER*S DISEASE | A/S FERROSAN (DK) | 1989-06-06 | — | — | US | disclosed |
| EP-0259621-A2 | Piperidine compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1988-03-16 | — | — | EP | disclosed |