SCHEMBL9702709

SCHEMBL9702709

C=C(C)C(=O)Oc1cccc(S(C)(=O)=O)c1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.39
ATM Q13315 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
KMT2A Q03164 2/20 0.33
EED O75530 1/20 0.33
BCAT2 O15382 1/20 0.33
BRD9 Q9H8M2 1/20 0.31
BAZ2B Q9UIF8 1/20 0.31
BAZ2A Q9UIF9 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA5A P35218 1/20 0.31
CA9 Q16790 1/20 0.31
MAPK1 P28482 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GCK P35557 1/20 0.31
LOX P28300 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ACHE P22303 1/20 0.30
TTR P02766 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6378399 0.78 L3MBTL1 (0.37) ELANECA1CA2CA5ACA9
SCHEMBL961161 0.78 CA1 (0.46) ELANEATMTDP1CA1CA2
SCHEMBL9703383 0.77 ALDH1A1 (0.40) ELANEKMT2ACA1CA2CA5A
SCHEMBL4519023 0.77 ELANE (0.46) ELANEATMTDP1KMT2ACA1
SCHEMBL31071497 0.76 HTR6 (0.46) TDP1EEDCA1CA2CA9
SCHEMBL17289480 0.76 ELANE (0.40) ELANEATMTDP1KMT2ACA1
SCHEMBL30509821 0.76 ELANE (0.45) ELANEATMTDP1KMT2ACA1
SCHEMBL246275 0.76 ELANE (0.45) ELANEATMTDP1KMT2ACA1
SCHEMBL2046110 0.75 ELANE (0.39) ELANEATMTDP1KMT2AMAPK1
SCHEMBL2340893 0.74 KDM4E (0.50) ELANETDP1KMT2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US claimed