Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.48 |
| ▸ | TK1 | P04183 | 5/20 | 0.42 |
| ▸ | TK2 | O00142 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | GYPA | P02724 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13415582 | 0.88 | CTSV (0.39) | RNASE1TK1CTSVCTSLCTSB | |
| SCHEMBL26233706 | 0.87 | RNASE1 (0.41) | RNASE1TK1TK2 | |
| SCHEMBL13396012 | 0.87 | CTSV (0.38) | RNASE1TK1TK2CTSVCTSL | |
| SCHEMBL2056807 | 0.86 | TK1 (0.44) | RNASE1TK1TK2 | |
| SCHEMBL21564054 | 0.86 | TK1 (0.44) | RNASE1TK1TK2 | |
| SCHEMBL6363668 | 0.85 | RNASE1 (0.45) | RNASE1TK1TK2PDE4DGYPA | |
| SCHEMBL7975895 | 0.82 | RNASE1 (0.50) | RNASE1TK1TK2PDE4D | |
| SCHEMBL26233701 | 0.81 | TK1 (0.43) | TK1 | |
| SCHEMBL31355237 | 0.80 | RNASE1 (0.72) | RNASE1TK1TK2 | |
| SCHEMBL7788368 | 0.80 | PDE4D (0.45) | RNASE1TK1TK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013869-A1 | METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM | GILEAD SCIENCES, INC. (US) | 1992-08-20 | — | — | WO | disclosed |