Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701904 | 0.88 | ADRA1A (0.58) | ADRA1ATAAR1MEN1KMT2AADRA2A | |
| SCHEMBL9702162 | 0.80 | TAAR1 (0.54) | TAAR1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL9700886 | 0.78 | CA12 (0.47) | ADRA1ATAAR1MEN1KMT2ACA2 | |
| SCHEMBL9701935 | 0.76 | TAAR1 (0.52) | TAAR1ALDH1A1CYP3A4 | |
| SCHEMBL11106092 | 0.75 | APLNR (0.49) | ADRA1ATAAR1APLNRMEN1KMT2A | |
| SCHEMBL9701633 | 0.75 | TAAR1 (0.57) | TAAR1 | |
| SCHEMBL13186651 | 0.74 | APLNR (0.56) | ADRA1ATAAR1APLNRMEN1KMT2A | |
| Methyl Alcohol SCHEMBL28318211 | 0.74 | APLNR (0.59) | ADRA1ATAAR1APLNRCA2ADRA2A | |
| SCHEMBL3027059 | 0.74 | APLNR (0.59) | ADRA1ATAAR1APLNRMEN1KMT2A | |
| SCHEMBL626051 | 0.74 | TAAR1 (0.73) | ADRA1ATAAR1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |