Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700877 | 0.83 | TAAR1 (0.39) | TAAR1ALDH1A1CYP1A2 | |
| SCHEMBL9701633 | 0.81 | TAAR1 (0.57) | TAAR1MAOBIDO1AGXTCTBP2 | |
| SCHEMBL9703429 | 0.79 | MAOB (0.49) | TAAR1MAOB | |
| SCHEMBL9701676 | 0.79 | KDM4E (0.56) | TAAR1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9702029 | 0.78 | TAAR1 (0.48) | TAAR1KDM4ECYP2C19ALDH1A1 | |
| SCHEMBL9701904 | 0.76 | ADRA1A (0.58) | TAAR1IDO1 | |
| SCHEMBL9702802 | 0.76 | ADRA1A (0.50) | TAAR1ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11493475 | 0.74 | LOXL2 (0.41) | TAAR1SMN1; SMN2 | |
| SCHEMBL18763976 | 0.73 | TAAR1 (0.52) | TAAR1MAOBHTTSMN1; SMN2KDM4E | |
| SCHEMBL6290388 | 0.73 | HTT (0.59) | TAAR1HTTSMN1; SMN2KDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |