Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702788 | 0.86 | TAAR1 (0.42) | TAAR1ALDH1A1GAAKMT2ATSHR | |
| SCHEMBL9702070 | 0.82 | TAAR1 (0.40) | TAAR1LMNASMN1; SMN2IDO1MAPT | |
| SCHEMBL9702802 | 0.80 | ADRA1A (0.50) | TAAR1ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9701904 | 0.80 | ADRA1A (0.58) | TAAR1IDO1KMT2AAOC3MEN1 | |
| SCHEMBL9701903 | 0.76 | TAAR1 (0.52) | TAAR1IDO1TSHR | |
| SCHEMBL8712496 | 0.73 | LMNA (0.58) | TAAR1LMNASMN1; SMN2IDO1MAPT | |
| SCHEMBL9701676 | 0.73 | KDM4E (0.56) | TAAR1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9702039 | 0.73 | SMN1; SMN2 (0.47) | TAAR1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11109543 | 0.72 | SMN1; SMN2 (0.53) | TAAR1LMNASMN1; SMN2IDO1MAPT | |
| SCHEMBL5719348 | 0.72 | LMNA (0.56) | TAAR1LMNASMN1; SMN2IDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |