Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337894 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1RAB9AMEN1GAAKMT2A | |
| SCHEMBL9703901 | 0.86 | SMN1; SMN2 (0.54) | CASP1ALDH1A1PKMTSHRRAB9A | |
| SCHEMBL8128764 | 0.83 | CASP1 (0.48) | CASP1ATMALDH1A1L3MBTL1PKM | |
| Hydrochloric Acid SCHEMBL10519969 | 0.81 | SMN1; SMN2 (0.39) | ALDH1A1TSHRRAB9AMEN1GAA | |
| SCHEMBL9703979 | 0.81 | MEN1 (0.38) | ALDH1A1TSHRRAB9AMEN1GAA | |
| Hydrochloric Acid SCHEMBL10518465 | 0.81 | NPSR1 (0.40) | ALDH1A1TSHRMAPTMEN1GAA | |
| Hydrochloric Acid SCHEMBL9503392 | 0.80 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1PKMTSHRRAB9A | |
| SCHEMBL9702139 | 0.80 | LMNA (0.41) | ALDH1A1TSHRPOLBMAPTMEN1 | |
| SCHEMBL10717053 | 0.79 | SLC6A2 (0.41) | ALDH1A1TSHRPOLBCYP1A2 | |
| SCHEMBL9503493 | 0.79 | CNR2 (0.39) | MEN1GAAKMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738977-A | 2-pyridylacetic acid derivatives, pharmaceutical composition containing the same and their use in treating ulcers | SUNTORY LIMITED (JP) | 1988-04-19 | — | — | US | claimed |
| EP-0223512-B1 | 2-PYRIDYLACETIC ACID DERIVATIVE, PREPARATION PROCESS THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4738977-A | 2-pyridylacetic acid derivatives, pharmaceutical composition containing the same and their use in treating ulcers | SUNTORY LIMITED (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0223512-A2 | 2-Pyridylacetic acid derivative, preparation process thereof and pharmaceutical composition containing the same | SUNTORY LIMITED (JP) | 1987-05-27 | — | — | EP | disclosed |