Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | MMP1 | P03956 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | MMP13 | P45452 | 7/20 | 0.58 |
| ▸ | MMP8 | P22894 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190555 | 0.84 | HTT (0.67) | HTTNPSR1MMP1PKMMMP13 | |
| SCHEMBL3250372 | 0.83 | PKM (0.64) | HTTNPSR1MMP1PKMMMP13 | |
| SCHEMBL6708168 | 0.83 | PKM (0.64) | HTTNPSR1MMP1PKMMMP13 | |
| SCHEMBL7082733 | 0.81 | MMP13 (0.70) | HTTNPSR1MMP1PKMMMP13 | |
| SCHEMBL9705169 | 0.81 | PKM (0.61) | HTTNPSR1MMP1PKMMMP13 | |
| SCHEMBL7080540 | 0.80 | HTT (0.62) | HTTNPSR1MMP1PKMMMP13 | |
| SCHEMBL7213584 | 0.80 | MMP13 (0.68) | HTTNPSR1MMP1PKMMMP13 | |
| SCHEMBL5602804 | 0.80 | HTT (1.00) | HTTNPSR1MMP1MMP13MMP8 | |
| SCHEMBL14468640 | 0.79 | PKM (0.59) | HTTNPSR1MMP1PKMMMP13 | |
| SCHEMBL11797251 | 0.79 | PKM (0.59) | HTTNPSR1MMP1PKMMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106718-A | Heat resistant relief structures | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | claimed |
| EP-0364949-A2 | Heat-stable positive photoresist | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | claimed |
| US-5106718-A | Heat resistant relief structures | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0364949-A2 | Heat-stable positive photoresist | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |