Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.61 |
| ▸ | MMP13 | P45452 | 8/20 | 0.59 |
| ▸ | MMP8 | P22894 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKLR | P30613 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708168 | 0.84 | PKM (0.64) | PKMMMP13MMP8HTTNPSR1 | |
| SCHEMBL3250372 | 0.84 | PKM (0.64) | PKMMMP13MMP8HTTNPSR1 | |
| SCHEMBL14468640 | 0.81 | PKM (0.59) | PKMMMP13MMP8HTTNPSR1 | |
| SCHEMBL9703007 | 0.81 | HTT (0.66) | PKMMMP13MMP8HTTNPSR1 | |
| SCHEMBL9109608 | 0.81 | PKM (0.59) | PKMMMP13MMP8HTTNPSR1 | |
| SCHEMBL11797251 | 0.81 | PKM (0.59) | PKMMMP13MMP8HTTNPSR1 | |
| SCHEMBL28593715 | 0.80 | PKM (0.53) | PKMMMP13MMP8HTTNPSR1 | |
| SCHEMBL11986342 | 0.79 | MMP13 (0.61) | PKMMMP13MMP8HTTNPSR1 | |
| SCHEMBL4195258 | 0.79 | MMP13 (0.66) | PKMMMP13MMP8HTTNPSR1 | |
| SCHEMBL7076712 | 0.79 | MMP13 (0.83) | PKMMMP13MMP8HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |