Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492985 | 0.85 | MAPT (0.49) | PSIP1MAPTHTR6ALDH1A1HSD11B1 | |
| SCHEMBL2334382 | 0.83 | MAPT (0.56) | PSIP1MAPTALDH1A1HSD11B1TDP1 | |
| SCHEMBL8940894 | 0.82 | MAPT (0.50) | PSIP1MAPTHTR6ALDH1A1HSD11B1 | |
| SCHEMBL11211587 | 0.79 | ALDH1A1 (0.60) | PSIP1MAPTALDH1A1CA1CA2 | |
| SCHEMBL2616457 | 0.79 | CA2 (0.59) | PSIP1MAPTHTR6ALDH1A1HSD11B1 | |
| SCHEMBL11306682 | 0.78 | MAPT (0.70) | PSIP1MAPTALDH1A1HSD11B1TDP1 | |
| SCHEMBL11895163 | 0.78 | MAPT (0.50) | PSIP1MAPTHTR6ALDH1A1HSD11B1 | |
| SCHEMBL15791835 | 0.78 | MAPT (0.70) | PSIP1MAPTALDH1A1HSD11B1TDP1 | |
| SCHEMBL3975244 | 0.76 | ALDH1A1 (0.59) | MAPTALDH1A1TDP1CA1CA2 | |
| SCHEMBL7927400 | 0.76 | MAPT (0.68) | PSIP1MAPTALDH1A1HSD11B1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106718-A | Heat resistant relief structures | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0364949-A2 | Heat-stable positive photoresist | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |