Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704275 | 1.00 | CTSL (0.49) | CTSLPREPITGB3ITGA2BKMT2A | |
| SCHEMBL7953092 | 0.79 | CTSL (0.47) | CTSLITGB3ITGA2BKMT2ACMA1 | |
| SCHEMBL24446555 | 0.75 | CTSL (0.48) | CTSLPREPITGB3ITGA2BKMT2A | |
| SCHEMBL6778071 | 0.74 | KMT2A (0.38) | CTSLITGB3ITGA2BKMT2A | |
| SCHEMBL5978676 | 0.74 | FKBP1A (0.40) | PREP | |
| SCHEMBL9699149 | 0.74 | PREP (0.61) | CTSLPREPCMA1ACE | |
| SCHEMBL28545846 | 0.74 | PREP (0.61) | CTSLPREPCMA1ACE | |
| SCHEMBL10882017 | 0.74 | PREP (0.61) | CTSLPREPCMA1ACE | |
| SCHEMBL7265704 | 0.74 | PREP (0.61) | CTSLPREPCMA1ACE | |
| SCHEMBL9775246 | 0.73 | MEN1 (0.43) | PREPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091427-A | PIPERAZINEDIONES HAVING A PSYCHOTROPIC ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |