Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 4/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705380 | 0.89 | PTH1R (0.50) | PTH1RLMNATP53BCHECES1 | |
| SCHEMBL9703671 | 0.85 | PTH1R (0.49) | PTH1RMAPTLMNAALDH1A1CCKBR | |
| SCHEMBL9702828 | 0.75 | CCKBR (0.48) | PGRCCKBRGABRA1GABRG2GABRB3 | |
| SCHEMBL8320572 | 0.72 | BRD4 (0.49) | PGRMAPTLMNAALDH1A1APAF1 | |
| SCHEMBL8316485 | 0.71 | BRD4 (0.46) | PGRMAPTLMNAALDH1A1APAF1 | |
| SCHEMBL8324826 | 0.68 | PTH1R (0.46) | PTH1RALDH1A1TP53BCHETSHR | |
| SCHEMBL9703566 | 0.66 | CCKBR (0.38) | ALDH1A1CYP1A2CYP2D6TSHRCCKBR | |
| SCHEMBL9703573 | 0.66 | CCKBR (0.55) | LMNACCKBRPDE3AGABRA1GABRG2 | |
| SCHEMBL28120473 | 0.64 | CCKBR (0.50) | LMNACCKBRPDE3AGABRA1GABRG2 | |
| SCHEMBL5426477 | 0.64 | ALDH1A1 (1.00) | MAPTALDH1A1APAF1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091381-A | Detection of peripheral benzodiazepine receptor activity in cell or tissue by labelled compounds using radioisotopes or cytoxic agents | BIOMEASURE, INC. (US) | 1992-02-25 | — | — | US | claimed |
| US-5091381-A | Detection of peripheral benzodiazepine receptor activity in cell or tissue by labelled compounds using radioisotopes or cytoxic agents | BIOMEASURE, INC. (US) | 1992-02-25 | — | — | US | disclosed |