Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703434 | 0.80 | MEN1 (0.56) | MEN1KMT2AHPGDMAPTPOLB | |
| SCHEMBL9703710 | 0.80 | LMNA (0.46) | MEN1KMT2AHPGDMAPTPOLB | |
| SCHEMBL9703465 | 0.78 | MAPT (0.48) | KMT2AMAPTPOLBALDH1A1PKM | |
| SCHEMBL9703469 | 0.78 | MAPT (0.48) | KMT2AMAPTPOLBALDH1A1PKM | |
| SCHEMBL30623198 | 0.78 | PKM (0.67) | MEN1KMT2AHPGDMAPTPOLB | |
| SCHEMBL9703402 | 0.78 | PKM (0.67) | MEN1KMT2AHPGDMAPTPOLB | |
| SCHEMBL30684288 | 0.78 | OPRK1 (0.43) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL26912419 | 0.78 | OPRK1 (0.43) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL20165830 | 0.77 | KMT2A (0.46) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL26215402 | 0.76 | MEN1 (0.69) | MEN1KMT2AHPGDMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |