Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 4/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704598 | 0.90 | STAT3 (0.50) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL9704619 | 0.90 | BAZ2B (0.40) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL9703378 | 0.89 | ADRB2 (0.45) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL9703892 | 0.89 | TOP2A (0.40) | ADRB2KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL9703785 | 0.85 | KDM4E (0.52) | KMT2AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9703871 | 0.83 | KDM4E (0.53) | ADRB2KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL9703747 | 0.83 | KDM4E (0.43) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL9705523 | 0.82 | ADRB2 (0.42) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL9704650 | 0.82 | KDM4E (0.43) | ADRB2STAT3KDM4EHPGDALDH1A1 | |
| SCHEMBL9703249 | 0.82 | KDM4E (0.45) | ADRB2STAT3KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4946844-A | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE CO., LTD. (JP) | 1990-08-07 | — | — | US | claimed |
| EP-0203795-B1 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4946844-A | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0323189-A2 | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE COMPANY LIMITED (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4720495-A | Benzo[ij]quinolizine-2-carboxylic acids useful for treating bacterial infection | TOKYO TANABE CO. LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0203795-A2 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |