Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703781 | 0.89 | ADRB2 (0.46) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL9704658 | 0.88 | ALDH1A1 (0.44) | KMT2AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9703919 | 0.83 | MEN1 (0.48) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL10646921 | 0.83 | MAOB (0.34) | ADRB2KDM4EALDH1A1HSD17B10CNR1 | |
| SCHEMBL9703608 | 0.83 | KDM4E (0.42) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL9704598 | 0.79 | STAT3 (0.50) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL9704619 | 0.79 | BAZ2B (0.40) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL5704396 | 0.78 | ADRB2 (0.64) | ADRB2STAT3KMT2AKDM4EHPGD | |
| SCHEMBL9703892 | 0.78 | TOP2A (0.40) | ADRB2KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL9703281 | 0.77 | KDM4E (0.39) | KDM4EHPGDALDH1A1HSD17B10CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203795-B1 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4720495-A | Benzo[ij]quinolizine-2-carboxylic acids useful for treating bacterial infection | TOKYO TANABE CO. LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0203795-A2 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |