Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.49 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703955 | 0.86 | HRH4 (0.43) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL8809531 | 0.84 | POLB (0.40) | LMNANQO2POLBTDP1ALDH1A1 | |
| SCHEMBL13850368 | 0.83 | HRH4 (0.50) | HRH4KMODYRK1ACDK9MEN1 | |
| SCHEMBL20537546 | 0.83 | HRH4 (0.50) | HRH4KMODYRK1ACDK9MEN1 | |
| SCHEMBL7675179 | 0.80 | HRH4 (0.56) | HRH4GLP1RDYRK1AMEN1KMT2A | |
| SCHEMBL5717618 | 0.78 | ALDH1A1 (0.67) | HRH4DYRK1ACDK9MEN1KMT2A | |
| SCHEMBL31137919 | 0.78 | ALDH1A1 (0.67) | HRH4DYRK1ACDK9MEN1KMT2A | |
| SCHEMBL1300470 | 0.76 | KMO (0.42) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL9703688 | 0.76 | NPC1 (0.45) | LMNAMEN1KMT2APOLBALDH1A1 | |
| 6,7-Dichloro-3-Hydroxy-2-Quinoxalinecarboxylic Acid SCHEMBL4287210 | 0.76 | GRIN2D (0.53) | GRIN2DGRIN3BLMNAGRIK1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |