Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GLP1R | P43220 | 2/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703856 | 0.86 | GRIN2D (0.49) | HRH4POLBGLP1RNQO2MMP1 | |
| SCHEMBL5189809 | 0.79 | HDAC6 (0.50) | HRH4NQO2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7675179 | 0.78 | HRH4 (0.56) | HRH4GLP1RNQO2MMP1MMP2 | |
| SCHEMBL9703948 | 0.76 | ATM (0.37) | GLP1RMMP1MMP2MMP3LMNA | |
| SCHEMBL6603312 | 0.73 | KCNMA1 (0.38) | POLBLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL4925379 | 0.73 | HRH4 (0.49) | HRH4GLP1RNQO2MMP1MMP2 | |
| SCHEMBL7679349 | 0.72 | POLB (0.43) | HRH4POLBNQO2HPGDPGK1 | |
| SCHEMBL20537546 | 0.71 | HRH4 (0.50) | HRH4KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL13850368 | 0.71 | HRH4 (0.50) | HRH4KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL9703688 | 0.70 | NPC1 (0.45) | POLBLMNAHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |