Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704330 | 0.82 | MAPK1 (0.45) | CFTRMAPK1CASP1CASP7MAPT | |
| SCHEMBL7261471 | 0.79 | CYP1A2 (0.56) | CYP1A2CFTRMAPTALDH1A1RAB9A | |
| SCHEMBL9703964 | 0.75 | MAPK1 (0.58) | CYP1A2MAPK1CASP1CASP7MAPT | |
| SCHEMBL9704918 | 0.74 | MAPK1 (0.50) | CYP1A2MAPK1CASP1CASP7MAPT | |
| SCHEMBL10466284 | 0.74 | CYP1A2 (0.48) | CYP1A2CFTRMAPTALDH1A1RAB9A | |
| SCHEMBL9703578 | 0.73 | MAPK1 (0.49) | CYP1A2MAPK1CASP1CASP7MAPT | |
| SCHEMBL9705722 | 0.73 | MAPK1 (0.49) | CYP1A2MAPK1CASP1CASP7MAPT | |
| SCHEMBL3964662 | 0.72 | MEN1 (0.53) | CYP1A2MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL6606816 | 0.72 | NLRP3 (0.59) | CYP1A2MAPK1CASP1CASP7MAPT | |
| SCHEMBL6275418 | 0.72 | RAB9A (0.47) | CYP1A2MAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |