Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703943 | 0.82 | CYP1A2 (0.52) | MAPK1CASP1CASP7MAPTLMNA | |
| SCHEMBL9704918 | 0.79 | MAPK1 (0.50) | MAPK1CASP1CASP7MAPTKDM4E | |
| SCHEMBL9703578 | 0.78 | MAPK1 (0.49) | MAPK1CASP1CASP7MAPTLMNA | |
| SCHEMBL9705722 | 0.78 | MAPK1 (0.49) | MAPK1CASP1CASP7MAPTLMNA | |
| SCHEMBL9703964 | 0.77 | MAPK1 (0.58) | MAPK1CASP1CASP7MAPTLMNA | |
| SCHEMBL6607610 | 0.74 | MAPT (0.47) | MAPTLMNAKDM4EHTTNPSR1 | |
| SCHEMBL6606816 | 0.74 | NLRP3 (0.59) | MAPK1CASP1CASP7MAPTLMNA | |
| SCHEMBL6970745 | 0.68 | PGK1 (0.50) | LMNAKDM4EHTTGAAALDH1A1 | |
| SCHEMBL6969528 | 0.68 | PGK1 (0.50) | LMNAKDM4EHTTGAAALDH1A1 | |
| SCHEMBL909516 | 0.67 | ALDH1A1 (0.66) | MAPTLMNAKDM4EHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |