Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704918 | 0.82 | MAPK1 (0.50) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL9703578 | 0.81 | MAPK1 (0.49) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL9705722 | 0.81 | MAPK1 (0.49) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL6606816 | 0.80 | NLRP3 (0.59) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL9704330 | 0.77 | MAPK1 (0.45) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL9703943 | 0.75 | CYP1A2 (0.52) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL8861179 | 0.74 | ALDH1A1 (0.70) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL9103612 | 0.71 | MAPK1 (0.62) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL6080442 | 0.71 | MAPK1 (0.51) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL9107325 | 0.71 | MAPK1 (0.61) | MAPK1CASP1CASP7ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |