Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588026 | 1.00 | ABCC9 (0.40) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL10510174 | 0.87 | ABCC9 (0.42) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL10510176 | 0.87 | ABCC9 (0.42) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL10510183 | 0.87 | ABCC9 (0.42) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9701739 | 0.86 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9589428 | 0.86 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9587967 | 0.83 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9589012 | 0.82 | ALDH1A1 (0.36) | CYP1A2CYP2C9CYP2C19LMNAPDK2 | |
| SCHEMBL9588271 | 0.82 | DRD2 (0.34) | ABCC9PDK2 | |
| SCHEMBL9588012 | 0.82 | IDO1 (0.34) | PDK2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489300-A2 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-10 | — | — | EP | disclosed |