Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703085 | 0.86 | OPRM1 (0.32) | DRD2DRD4ABCC9 | |
| SCHEMBL9588575 | 0.86 | OPRM1 (0.32) | DRD2DRD4ABCC9 | |
| SCHEMBL9589012 | 0.85 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1PDK2 | |
| SCHEMBL9588012 | 0.85 | IDO1 (0.34) | MAPTNPSR1PDK2 | |
| SCHEMBL9588419 | 0.85 | F10 (0.33) | DRD2ABCC9MEN1KMT2AALDH1A1 | |
| SCHEMBL9702059 | 0.84 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL9587643 | 0.84 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL9587842 | 0.83 | MEN1 (0.41) | MEN1KMT2AALDH1A1MAPTPDK2 | |
| SCHEMBL9701823 | 0.83 | MEN1 (0.41) | MEN1KMT2AALDH1A1MAPTPDK2 | |
| SCHEMBL9588559 | 0.82 | HSD17B1 (0.34) | MEN1KMT2AMAPTCACNA1CF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272170-A | Tetralones with pharmacological activity | J. URIACH & CIA., S.A. (ES) | 1993-12-21 | — | — | US | disclosed |
| US-5208246-A | Hypotensive, bronchodilator | J. URIACH & CIA. (ES) | 1993-05-04 | — | — | US | disclosed |
| EP-0489300-A2 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-10 | — | — | EP | disclosed |