Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318008 | 0.83 | DDAH1 (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL10439327 | 0.81 | PARP1 (0.40) | PARP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9704776 | 0.81 | PI4KA (0.46) | PARP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8641790 | 0.79 | PARP1 (0.39) | PARP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9705920 | 0.78 | PRMT5 (0.41) | PARP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL31586691 | 0.75 | SMN1; SMN2 (0.39) | NOS3NOS1NOS2ALDH1A1MAPK1 | |
| SCHEMBL7853172 | 0.75 | HPGD (0.46) | PI4KAPI4K2BPI4K2API4KBNOS3 | |
| SCHEMBL8326986 | 0.74 | NOS1 (0.54) | NOS3NOS1NOS2POLB | |
| SCHEMBL9704371 | 0.72 | SMN1; SMN2 (0.48) | ALDH1A1MAPK1 | |
| SCHEMBL7850823 | 0.72 | NOS3 (0.38) | PI4KAPI4K2BPI4K2API4KBNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |