Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9090094 | 0.90 | ADORA1 (0.40) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL10439327 | 0.84 | PARP1 (0.40) | PI4KAPI4K2BPI4K2API4KBPARP1 | |
| SCHEMBL9703975 | 0.81 | PARP1 (0.40) | PI4KAPI4K2BPI4K2API4KBPARP1 | |
| SCHEMBL8641790 | 0.79 | PARP1 (0.39) | PI4KAPI4K2BPI4K2API4KBPARP1 | |
| SCHEMBL9705920 | 0.78 | PRMT5 (0.41) | PI4KAPI4K2BPI4K2API4KBPARP1 | |
| SCHEMBL9704690 | 0.75 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL8326986 | 0.74 | NOS1 (0.54) | POLBNOS3NOS1NOS2 | |
| SCHEMBL9851422 | 0.73 | MARS2 (0.41) | KMT2AKDM4ENOS3NOS1NOS2 | |
| SCHEMBL8144258 | 0.73 | MAPT (0.60) | PARP1MAPTPKMKMT2AKDM4E | |
| SCHEMBL9705274 | 0.72 | NOS3 (0.48) | PI4KAPI4K2BPI4K2API4KBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |