Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | RET | P07949 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
| ▸ | PRKACA | P17612 | 1/20 | 0.59 |
| ▸ | LTK | P29376 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255700 | 0.89 | CHEK1 (0.49) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL2843606 | 0.76 | CHEK1 (0.61) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL1192489 | 0.74 | CHEK1 (0.59) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL8018832 | 0.74 | CHEK1 (0.59) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL22412847 | 0.74 | CHEK1 (0.59) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL968490 | 0.74 | DYRK1A (1.00) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL30958678 | 0.74 | CHEK1 (0.59) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL12559905 | 0.74 | CHEK1 (0.59) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL29365779 | 0.74 | DYRK1A (1.00) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL2919086 | 0.71 | DYRK1A (0.45) | CHEK1AURKADAPK3JAK2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146226-A | Pyrrolo [2,3-d ] pyrimidine compound with nitrogen-containing heterocyclic structure, and preparation method and application thereof | 贵州大学 | 2024-06-07 | — | — | CN | claimed |
| CN-122036605-A | Antagonists of GPR39 proteins | 俄勒冈健康科学大学 | 2026-05-15 | — | — | CN | disclosed |
| US-20260132147-A1 | BAX INHIBITORS AND USES THEREOF | CASE WESTERN RESERVE UNIV (US) | 2026-05-14 | — | — | US | disclosed |
| US-12479857-B2 | Bax inhibitors and uses thereof | CASE WESTERN RESERVE UNIVERSITY (US) | 2025-11-25 | — | — | US | disclosed |
| US-20250282785-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2025-09-11 | — | — | US | disclosed |
| US-12390463-B2 | Dosage forms and regimens for amino acid compounds | PLIANT THERAPEUTICS, INC. (US) | 2025-08-19 | — | — | US | disclosed |
| US-20250223288-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2025-07-10 | — | — | US | disclosed |
| EP-4522608-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2025-03-19 | — | — | EP | disclosed |
| EP-4520329-A2 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | Pliant Therapeutics, Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| EP-4509512-A2 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2025-02-19 | — | — | EP | disclosed |
| EP-0370704-A2 | Aralkylamine derivatives, preparation thereof and fungicides containing the same | UBE INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
| EP-0196524-B1 | PHENOXYALKYLAMINOPYRIMIDINE DERIVATIVES, THEIR PREPARATION AND INSECTICIDAL AND ACARICIDAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4845097-A | AGRICULTURE | SANKYO COMPANY LIMITED (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0103114-B1 | THIENOPYRIDINE DERIVATIVES, THEIR PREPARATION AND INSECTICIDAL AND ACARICIDAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1986-11-12 | — | — | EP | disclosed |
| EP-0196524-A2 | Phenoxyalkylaminopyrimidine derivatives, their preparation and insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4562193-A | 4-[2-(Di- or trisubstitutedphenoxy)ethyl amino]thienodipyrimidines and insecticidal and acaricidal composition containing said pyrimidines | SANKYO COMPANY LIMITED (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0103114-A2 | Thienopyridine derivatives, their preparation and insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1984-03-21 | — | — | EP | disclosed |
| US-4256738-A | BACTERICIDES, PYRIMIDINYL, QUINAZOLINYL | BOEHRINGER INGELHEIM GMBH (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4196207-A | Process for controlling eradicating or preventing infestations of animals by Ixodid ticks | ICI AUSTRALIA LIMITED | 1980-04-01 | — | — | US | disclosed |
| US-4146716-A | PLANT GROWTH REGULATORS, FUNGICIDES, BACTERICIDES, VIRICIDES, INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132147-A1 | BAX INHIBITORS AND USES THEREOF | BAX, BCL2, BAK1 | CHEK1 326/4885AURKA 3878/4885DAPK3 108/4885 |
| US-12390463-B2 | Dosage forms and regimens for amino acid compounds | ITGB6, ITGA6, ITGAV | CHEK1 3817/4885AURKA 3839/4885DAPK3 3807/4885 |
| US-20250223288-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | ITGB6, ITGA6, ITGA5 | CHEK1 3709/4885AURKA 3420/4885DAPK3 2805/4885 |
| US-20250282785-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | NFKBIA, IKBKG, IKBKB | CHEK1 1018/4885AURKA 3029/4885DAPK3 49/4885 |
| US-12479857-B2 | Bax inhibitors and uses thereof | BAX, TMBIM6, BCL2 | CHEK1 299/4885AURKA 2706/4885DAPK3 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.