Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 13/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704072 | 1.00 | KMT2A (0.48) | KMT2AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL8135626 | 0.88 | ALDH1A1 (0.58) | KMT2AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL9704235 | 0.87 | MAPT (0.53) | KMT2AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL9704228 | 0.87 | MAPT (0.53) | KMT2AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL9705730 | 0.86 | KMT2A (0.50) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL9705734 | 0.86 | KMT2A (0.50) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL9704444 | 0.80 | MAPT (0.56) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL9704448 | 0.80 | MAPT (0.56) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL8139487 | 0.79 | ALDH1A1 (0.58) | KMT2AMAPTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8135625 | 0.78 | KCNMA1 (0.55) | KMT2AMAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |