Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705734 | 1.00 | KMT2A (0.50) | KMT2AMEN1PKMMAPTTHRB | |
| SCHEMBL7976022 | 0.89 | GPR35 (0.57) | KMT2AMEN1PKMMAPTTHRB | |
| SCHEMBL9704079 | 0.86 | KMT2A (0.48) | KMT2AMEN1PKMMAPTKCNMA1 | |
| SCHEMBL9704072 | 0.86 | KMT2A (0.48) | KMT2AMEN1PKMMAPTKCNMA1 | |
| SCHEMBL9704228 | 0.84 | MAPT (0.53) | KMT2APKMMAPTKCNMA1MAPK1 | |
| SCHEMBL9704235 | 0.84 | MAPT (0.53) | KMT2APKMMAPTKCNMA1MAPK1 | |
| SCHEMBL9364671 | 0.80 | GPR35 (0.60) | KMT2AMEN1PKMMAPTTHRB | |
| SCHEMBL9364653 | 0.80 | KCNMA1 (0.58) | KMT2AMEN1PKMMAPTTHRB | |
| SCHEMBL9703998 | 0.78 | MAPK1 (0.59) | KMT2AMEN1PKMMAPTTHRB | |
| SCHEMBL9704003 | 0.78 | MAPK1 (0.59) | KMT2AMEN1PKMMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |