SCHEMBL9704119

SCHEMBL9704119

CCCc1ccc(-c2ccc(CCC(=O)NN)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 2/20 0.51
HDAC8 Q9BY41 2/20 0.51
CTSD P07339 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HIF1A Q16665 1/20 0.48
HDAC1 Q13547 2/20 0.46
MCL1 Q07820 1/20 0.46
GAA P10253 1/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4416871 0.81 FFAR1 (0.51) HDAC2HDAC8CYP1A2CYP3A4CYP2D6
SCHEMBL6037022 0.78 HDAC2 (0.62) HDAC2HDAC8CYP1A2CYP3A4CYP2D6
SCHEMBL4411258 0.77 MAPT (0.54) GAAALDH1A1FFAR1L3MBTL1ACACB
SCHEMBL2836138 0.77 CYP3A4 (0.53) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL17967143 0.77 HDAC1 (0.57) HDAC2HDAC8CYP1A2CYP3A4CYP2D6
SCHEMBL8532525 0.77 CYP1A2 (0.51) HDAC2HDAC8CYP1A2CYP3A4CYP2D6
SCHEMBL27606163 0.77 LMNA (0.53) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL26497798 0.76 ALDH1A1 (0.48) HDAC2HDAC8CTSDCYP1A2CYP3A4
SCHEMBL13903016 0.76 ALDH1A1 (0.67) ALDH1A1L3MBTL1HPGD
SCHEMBL967387 0.76 HDAC2 (0.68) HDAC2HDAC8CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5143642-A Thiadiazoles MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-09-01 US disclosed