Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604068 | 0.91 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL6604320 | 0.84 | TSHR (0.48) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL6375213 | 0.84 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL6602730 | 0.81 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL30623229 | 0.81 | ADORA3 (0.55) | ALDH1A1HPGDKMT2AADORA3 | |
| SCHEMBL9704059 | 0.81 | ADORA3 (0.55) | ALDH1A1HPGDKMT2AADORA3 | |
| SCHEMBL9704290 | 0.81 | GRIN2D (0.55) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL6604565 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL6602046 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL9704461 | 0.79 | LMNA (0.43) | KDM4EALDH1A1HPGDHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |