SCHEMBL9704480

SCHEMBL9704480

O=C1[N]CCCN1Cc1ccc(O)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
HRH3 Q9Y5N1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9704138 0.90 ERCC1 (0.39)
SCHEMBL5982177 0.83 L3MBTL1 (0.54) L3MBTL1
SCHEMBL9705894 0.82 BCL2L1 (0.39) L3MBTL1
SCHEMBL9705989 0.80 GAA (0.52) SMN1; SMN2HRH3
SCHEMBL9293223 0.75 L3MBTL1 (0.65) L3MBTL1HRH3
SCHEMBL5543146 0.75 ERCC1 (0.46) SMN1; SMN2
SCHEMBL5539260 0.73 ALDH1A1 (0.56) L3MBTL1SMN1; SMN2
SCHEMBL11759154 0.73 L3MBTL1 (0.73) L3MBTL1SMN1; SMN2HRH3
SCHEMBL5540694 0.73 ALDH1A1 (0.42) SMN1; SMN2
SCHEMBL9704338 0.73 ERCC1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470543-A1 Heterocyclic imidazoles, remedies containing them and processes for their preparation Dr. Karl Thomae GmbH (DE) 1992-02-12 EP disclosed