Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 4/20 | 0.37 |
| ▸ | CD74 | P04233 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704692 | 0.91 | BCL2L1 (0.40) | BCL2L1BRD4HTR1BMEN1POLB | |
| SCHEMBL9704480 | 0.82 | L3MBTL1 (0.41) | L3MBTL1 | |
| SCHEMBL5982177 | 0.82 | L3MBTL1 (0.54) | MEN1POLBKMT2ACYP2C9CYP2C19 | |
| SCHEMBL9704364 | 0.80 | CMA1 (0.54) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL15152924 | 0.78 | L3MBTL1 (0.58) | POLBKMT2AL3MBTL1 | |
| SCHEMBL8799328 | 0.77 | L3MBTL1 (0.65) | KMT2AMIFCD74L3MBTL1 | |
| SCHEMBL29872721 | 0.75 | L3MBTL1 (0.68) | KMT2ACYP2C9MIFCD74L3MBTL1 | |
| SCHEMBL5548109 | 0.74 | ALDH1A1 (0.50) | MEN1POLBKMT2AL3MBTL1CHRM2 | |
| SCHEMBL5537145 | 0.74 | SMN1; SMN2 (0.50) | BRD4MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL5539504 | 0.74 | MAPT (0.60) | MEN1KMT2AMAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |