Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3256270 | 0.82 | PLCG1 (0.58) | CA1CA2MMP2MMP9MMP1 | |
| Fluoresone SCHEMBL24999 | 0.80 | PSIP1 (0.58) | CA1CA2MMP2MMP9MMP1 | |
| SCHEMBL15199478 | 0.80 | MMP2 (0.46) | CA1CA2MMP2MMP9MMP1 | |
| SCHEMBL3108160 | 0.78 | PSEN1 (0.46) | CA1CA2MMP2MMP9MMP1 | |
| SCHEMBL14544901 | 0.78 | MMP2 (0.45) | CA1CA2MMP2MMP9MMP1 | |
| SCHEMBL15013716 | 0.78 | ALDH1A1 (0.56) | CA1CA2MMP2MMP9MMP1 | |
| SCHEMBL8395368 | 0.77 | PSIP1 (0.61) | CA1CA2MMP2ALDH1A1HSD11B1 | |
| SCHEMBL9704914 | 0.75 | PLCG1 (0.70) | CA1CA2MMP2MMP9MMP1 | |
| SCHEMBL8789025 | 0.75 | ALDH1A1 (0.56) | CA1CA2MMP2MMP9MMP1 | |
| SCHEMBL8788972 | 0.75 | ALDH1A1 (0.64) | CA1CA2MMP2MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |