Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702850 | 0.85 | AR (0.36) | ARLMNASMN1; SMN2 | |
| SCHEMBL10396553 | 0.83 | CARM1 (0.37) | AR | |
| SCHEMBL2764978 | 0.83 | BCL2 (0.35) | KMT2A | |
| SCHEMBL9701890 | 0.82 | XIAP (0.40) | XIAPARSLC6A4HTR2AKCNH2 | |
| SCHEMBL9702388 | 0.76 | XIAP (0.45) | XIAPARSLC6A4HTR2AKCNH2 | |
| SCHEMBL8845542 | 0.71 | LTA4H (0.40) | KMT2A | |
| SCHEMBL8341904 | 0.70 | ALDH1A1 (0.37) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL9636852 | 0.70 | NPY5R (0.32) | — | |
| SCHEMBL9777726 | 0.68 | CYP1A2 (0.38) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL9704630 | 0.67 | AR (0.38) | ARSLC6A4HTR2AKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481921-A1 | Substituted carbodiimides and thio-ureas and their utilisation against insects | CIBA-GEIGY AG (CH) | 1992-04-22 | — | — | EP | claimed |
| EP-0481921-A1 | Substituted carbodiimides and thio-ureas and their utilisation against insects | CIBA-GEIGY AG (CH) | 1992-04-22 | — | — | EP | disclosed |