Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683231 | 0.87 | EIF4E (0.47) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL22749364 | 0.85 | KMT2A (0.43) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL7688039 | 0.84 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL9299730 | 0.84 | MAPT (0.41) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL1567614 | 0.80 | NPC1 (0.53) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL707416 | 0.78 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL31191383 | 0.78 | MAPK1 (0.48) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL1275645 | 0.78 | MAPK1 (0.48) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL3158027 | 0.78 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL2323726 | 0.77 | HPD (0.59) | MEN1KMT2AMAPTHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506907-A1 | HETEROCYCLIC DIONE DERIVATIVES AS PESTICIDES AND PLANT GROWTH REGULATORS | SANDOZ-ERFINDUNGEN Verwaltungsgesellschaft m.b.H. (AT) | 1992-10-07 | — | — | EP | disclosed |
| WO-1992007837-A1 | HETEROCYCLIC DIONE DERIVATIVES AS PESTICIDES AND PLANT GROWTH REGULATORS | SANDOZ LTD. (CH) | 1992-05-14 | — | — | WO | disclosed |