Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11184838 | 0.78 | LMNA (0.39) | LMNADNM1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL1038114 | 0.78 | LMNA (0.42) | LMNADNM1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL190294 | 0.78 | LMNA (0.42) | LMNADNM1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL268149 | 0.78 | DNM1 (0.39) | LMNADNM1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL8749793 | 0.76 | LMNA (0.43) | LMNADNM1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL30807210 | 0.76 | LMNA (0.43) | LMNADNM1ALDH1A1HSD17B10MEN1 | |
| Fluoride SCHEMBL3259338 | 0.76 | LMNA (0.41) | LMNADNM1SMN1; SMN2ALDH1A1HSD17B10 | |
| Fluoride SCHEMBL11099490 | 0.76 | LMNA (0.46) | LMNADNM1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL28664945 | 0.75 | DNM1 (0.40) | DNM1TSHRCA12CA1CA2 | |
| SCHEMBL11864376 | 0.75 | LMNA (0.41) | LMNADNM1ALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214852-B1 | PERFLUOROAMINOETHERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5049670-A | Pour point | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-09-17 | — | — | US | disclosed |
| US-4929725-A | NONFLAMMABLE, HYDRAULIC FLUIDS | MOORE GEORGE G I (US) | 1990-05-29 | — | — | US | disclosed |
| US-4788339-A | HIGH BOILING, LOW POUR POINT; HYDRAULIC FLUIDS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0214852-A2 | Perfluoroaminoethers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |