SCHEMBL268149

SCHEMBL268149

CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)C(CC)N(CO)CO

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 6/20 0.39
LMNA P02545 3/20 0.37
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
GBA1 P04062 1/20 0.34
GGPS1 O95749 3/20 0.34
MGLL Q99685 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL190294 0.88 LMNA (0.42) DNM1LMNATSHRALDH1A1HSD17B10
SCHEMBL1038114 0.88 LMNA (0.42) DNM1LMNATSHRALDH1A1HSD17B10
Fluoride SCHEMBL11099490 0.86 LMNA (0.46) DNM1LMNATSHRALDH1A1HSD17B10
Fluoride SCHEMBL3259338 0.86 LMNA (0.41) DNM1LMNATSHRALDH1A1HSD17B10
Fluoride SCHEMBL11097713 0.82 LMNA (0.43) DNM1LMNATSHRALDH1A1HSD17B10
Avridine SCHEMBL6741009 0.80 LMNA (0.35) DNM1LMNATSHRALDH1A1HSD17B10
SCHEMBL23288549 0.78 DNM1 (0.37) DNM1LMNATSHRALDH1A1HSD17B10
SCHEMBL20590751 0.78 DNM1 (0.48) DNM1TSHRALDH1A1CA12CA1
SCHEMBL10380685 0.78 DNM1 (0.42) DNM1TSHRCA12CA1CA2
SCHEMBL9705202 0.78 LMNA (0.41) DNM1LMNATSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030450-B2 Canine RANKL and methods for preparing and using the same INTERVET INC. (US) 2011-10-04 US claimed
US-20090148456-A1 CANINE RANKL AND METHODS FOR PREPARING AND USING THE SAME SCHERING-PLOUGH ANIMAL HEALTH CORPORATION 2009-06-11 US claimed
EP-1578305-A4 CANINE RANKL AND METHODS FOR PREPARING AND USING THE SAME SCHERING PLOUGH LTD (CH) 2008-08-27 EP claimed
US-7417122-B2 Mammalian galanin receptors SCHERING CORPORATION (US) 2008-08-26 US claimed
US-20070255044-A1 MAMMALIAN GALANIN RECEPTORS SCHERING CORPORATION 2007-11-01 US claimed
US-20060154858-A1 Canine rankl and methods for preparing and using the same SCHERING-PLOUGH LTD. (CH) 2006-07-13 US claimed
EP-1578305-A2 CANINE RANKL AND METHODS FOR PREPARING AND USING THE SAME Schering-Plough Ltd. (CH) 2005-09-28 EP claimed
WO-2004052233-A2 CANINE RANKL AND METHODS FOR PREPARING AND USING THE SAME SCHERING-PLOUGH LTD. (CH) 2004-06-24 WO claimed
US-20220155305-A1 METHODS OF TREATING AND DIAGNOSING LUNG CANCER YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-05-19 US disclosed
US-20210315983-A1 VACCINATION WITH CANCER NEOANTIGENS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-10-14 US disclosed
US-20210095007-A1 ANTIBODIES THAT BIND EBOLA GLYCOPROTEIN AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2021-04-01 US disclosed
US-10894818-B2 Antibodies that bind Ebola glycoprotein and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-01-19 US disclosed
US-10463747-B2 Method of developing a vaccine using peptide-poly IC complexes H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2019-11-05 US disclosed
US-10202617-B2 Expression cassette for efficient surface display of antigenic proteins TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2019-02-12 US disclosed
EP-0521318-A2 Hepatitis C diagnostics and vaccines LUCKY LTD. (KR) 1993-01-07 EP disclosed
EP-0506826-A1 ANTIBODY ANTAGONISTS OF HUMAN INTERLEUKIN-4. SCHERING CORP (US) 1992-10-07 EP disclosed
WO-1992006115-A1 ANTAGONISTS OF HUMAN GAMMA INTERFERON SCHERING CORPORATION (US) 1992-04-16 WO disclosed
EP-0439056-A2 Coccidiosis vaccines F. HOFFMANN-LA ROCHE AG (CH) 1991-07-31 EP disclosed
WO-1991009059-A1 ANTIBODY ANTAGONISTS OF HUMAN INTERLEUKIN-4 SCHERING CORPORATION (US) 1991-06-27 WO disclosed
EP-0344808-A1 Recombinant coccidiosis vaccines F. HOFFMANN-LA ROCHE AG (CH) 1989-12-06 EP disclosed