Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | CTSE | P14091 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705257 | 1.00 | REN (0.46) | RENCTSDCTSECTSKCTSS | |
| SCHEMBL9741069 | 0.89 | REN (0.47) | RENCTSDCTSECTSKCTSS | |
| SCHEMBL9741074 | 0.89 | REN (0.47) | RENCTSDCTSECTSKCTSS | |
| SCHEMBL9740133 | 0.84 | REN (0.41) | RENCTSDCTSECTSKCTSS | |
| SCHEMBL9740136 | 0.84 | REN (0.41) | RENCTSDCTSECTSKCTSS | |
| SCHEMBL7316703 | 0.83 | POLB (0.43) | CTSKPOLBCNR2KCNH2 | |
| SCHEMBL7316693 | 0.83 | POLB (0.43) | CTSKPOLBCNR2KCNH2 | |
| SCHEMBL6577311 | 0.82 | CA1 (0.40) | CTSKCTSSCNR2 | |
| SCHEMBL9725752 | 0.80 | CA1 (0.44) | RENCTSKCTSSCNR2AAK1 | |
| SCHEMBL7295320 | 0.80 | CA1 (0.44) | RENCTSKCTSSCNR2AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487980-A1 | Aminodiols-derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-03 | — | — | EP | disclosed |