Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705236 | 0.89 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9705120 | 0.79 | POLB (0.43) | KMT2ASMN1; SMN2MAPTHTTPOLB | |
| SCHEMBL9782227 | 0.77 | — | — | |
| SCHEMBL9704716 | 0.77 | P2RX1 (0.36) | POLB | |
| SCHEMBL7171235 | 0.72 | ALDH1A1 (0.42) | SMN1; SMN2MAPTHTTPOLB | |
| SCHEMBL9704424 | 0.69 | POLB (0.41) | KMT2ASMN1; SMN2MAPTHTTPOLB | |
| SCHEMBL29905921 | 0.68 | ITGB1 (0.39) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL11586051 | 0.65 | ALDH1A1 (0.54) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL8754886 | 0.65 | LMNA (0.53) | MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11728865 | 0.64 | ALDH1A1 (0.33) | MEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |