Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705120 | 0.86 | POLB (0.43) | P2RX1P2RX4P2RX3BCHEHTR1A | |
| SCHEMBL9704424 | 0.77 | POLB (0.41) | P2RX1P2RX4P2RX3BCHEHTR1A | |
| SCHEMBL7171235 | 0.73 | ALDH1A1 (0.42) | POLBALDH1A1HPGD | |
| SCHEMBL11506548 | 0.63 | HTR1A (0.74) | P2RX1P2RX4P2RX3CA12CA2 | |
| SCHEMBL7507360 | 0.63 | POLB (0.78) | P2RX1P2RX4P2RX3TP53POLB | |
| SCHEMBL11506428 | 0.61 | SIGMAR1 (0.53) | P2RX1P2RX4P2RX3CA12CA2 | |
| SCHEMBL12472375 | 0.61 | POLB (0.64) | HTR1APOLBTSHR | |
| SCHEMBL14230000 | 0.59 | TACR1 (0.49) | BCHECA12CA9HTR1ATACR1 | |
| SCHEMBL7511116 | 0.57 | CNR2 (0.39) | CA12CA2CA9HTR1ATACR1 | |
| SCHEMBL3468211 | 0.57 | CA12 (0.57) | P2RX1P2RX4P2RX3CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |