Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 3/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22061852 | 0.88 | CTSL (0.52) | CTSLCTSBCTSKUSP7KMT2A | |
| SCHEMBL19357687 | 0.78 | UCHL1 (0.49) | CTSLCTSBCTSKUSP7TEAD1 | |
| SCHEMBL19357728 | 0.77 | TEAD1 (0.47) | CTSLCTSBCTSKUSP7TEAD1 | |
| SCHEMBL29710088 | 0.77 | TEAD1 (0.47) | CTSLCTSBCTSKUSP7TEAD1 | |
| SCHEMBL19357626 | 0.75 | TEAD1 (0.46) | CTSLCTSBCTSKUSP7TEAD1 | |
| SCHEMBL2327219 | 0.74 | MAOA (0.52) | CTSLCTSBCTSKUSP7KMT2A | |
| SCHEMBL30043742 | 0.74 | MAOA (0.52) | CTSLCTSBCTSKUSP7KMT2A | |
| SCHEMBL19375056 | 0.72 | TEAD1 (0.43) | CTSLCTSBCTSKUSP7KMT2A | |
| SCHEMBL20608442 | 0.71 | UCHL1 (0.46) | USP7TEAD1TEAD4TEAD2TEAD3 | |
| SCHEMBL13939593 | 0.69 | KMT2A (0.48) | KMT2AADRA1DADRA1AADRA1BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192034-B1 | DIBENZAZEPINE DERIVATIVES, THEIR PREPARATION, STARTING MATERIALS FOR THEIR PREPARATION, AND USE OF THE DIBENZAZEPINE DERIVATIVES AS PESTICIDES | CIBA-GEIGY AG (CH) | 1992-07-15 | — | — | EP | claimed |
| US-4833245-A | CHEMICAL INTERMEDIATES FOR INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-05-23 | — | — | US | claimed |
| EP-0192034-A2 | Dibenzazepine derivatives, their preparation, starting materials for their preparation, and use of the dibenzazepine derivatives as pesticides | CIBA-GEIGY AG (CH) | 1986-08-27 | — | — | EP | claimed |
| EP-0192034-B1 | DIBENZAZEPINE DERIVATIVES, THEIR PREPARATION, STARTING MATERIALS FOR THEIR PREPARATION, AND USE OF THE DIBENZAZEPINE DERIVATIVES AS PESTICIDES | CIBA-GEIGY AG (CH) | 1992-07-15 | — | — | EP | disclosed |
| US-5015640-A | Insecticides or miticides | CIBA-GEIGY CORPORATION (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0368176-A1 | Esters of carboximidic acid, their preparation, and their use as pesticides | CIBA-GEIGY AG (CH) | 1990-05-16 | — | — | EP | disclosed |
| US-4833245-A | CHEMICAL INTERMEDIATES FOR INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4766115-A | 5,6-dihydro-6H-dibenz[c,e]azepine-6-(thio)carboximidic acid esters and insecticidal use thereof | HOFFMANN-LA ROCHE INC. (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0192034-A2 | Dibenzazepine derivatives, their preparation, starting materials for their preparation, and use of the dibenzazepine derivatives as pesticides | CIBA-GEIGY AG (CH) | 1986-08-27 | — | — | EP | disclosed |