Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 9/20 | 0.42 |
| ▸ | PNP | P00491 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699248 | 0.84 | XDH (0.61) | XDHPNP | |
| SCHEMBL22901881 | 0.79 | PI4KA (0.47) | XDHPNPALDH1A1 | |
| SCHEMBL3759472 | 0.76 | XDH (0.70) | XDHPNPALDH1A1KDM4E | |
| SCHEMBL8302 | 0.73 | XDH (0.39) | XDHPNPALDH1A1 | |
| SCHEMBL13717310 | 0.72 | AHCY (0.40) | — | |
| SCHEMBL3291325 | 0.70 | CDK1 (0.47) | XDHALDH1A1 | |
| SCHEMBL9001851 | 0.70 | XDH (0.37) | XDHPNPALDH1A1 | |
| SCHEMBL29159183 | 0.70 | ALDH1A1 (0.37) | XDHPNPALDH1A1 | |
| SCHEMBL6699970 | 0.70 | PI4KA (0.59) | — | |
| SCHEMBL1746164 | 0.69 | TK1 (0.37) | XDHPNPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | claimed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |